Evaluation of Phytocompounds Obtained from Catharanthus Roseus to Target the Upregulated MMPs in Prostate Cancer

Every year over 1.5 million men develop prostate cancer and it is also a significant cause of mortality among men. There are multiple factors upregulating cancer, which includes mutation in the genetics, ethnicity or hereditary. Out 23 MMPs, there 4 MMPs mostly upregulated cancer. function by deteriorating several proteins present extracellular matrix. Catharanthus roseus medicinal plant has antidiabetic, anticancer, antispasmodic antihypertensive properties. So, prime focus study to identify phytochemicals that potent against usually i.e., MMP9, MMP1, MMP10, MMP13 via static simulation having lesser no side effects.